Investigations on Polyol Derivatives. I.

Crystallographic investigations of biotin and carboxybiotin derivatives.

The structures of a family of biotin and carboxybiotin derivatives have provided information on the mechanism of biotin action. The ureido moiety of the uncarboxylated cofactor is polarized and able to interact with ions and polar molecules; intermolecular interactions in the biotin derivatives suggest biochemical mechanisms resulting in nucleophilic activation to the enol tautomer. N1' carboxy...

Structural investigations on native collagen type I fibrils using AFM.

This study was carried out to determine the elastic properties of single collagen type I fibrils with the use of atomic force microscopy (AFM). Native collagen fibrils were formed by self-assembly in vitro characterized with the AFM. To confirm the inner assembly of the collagen fibrils, the AFM was used as a microdissection tool. Native collagen type I fibrils were dissected and the inner core...

The Effect of Temperature on Kinetics and Diffusion Coefficients of Metallocene Derivatives in Polyol-Based Deep Eutectic Solvents.

The temperature dependence of the density, dynamic viscosity and ionic conductivity of several deep eutectic solvents (DESs) containing ammonium-based salts and hydrogen bond donvnors (polyol type) are investigated. The temperature-dependent electrolyte viscosity as a function of molar conductivity is correlated by means of Walden's rule. The oxidation of ferrocene (Fc/Fc+) and reduction of cob...

Polyol Laxative Threshold Value

Ninhydrin-based Forensic Investigations I. Fingerprints

Ninhydrin reagents are currently used for amino acid determination. However, ninhydrin reacts with amino groups of amino acids and other components of palmar sweat to develop Ruheman’s purple. Therefore, it was used on a large scale to fingerprint development. Another recent application of ninhydrin is related to trace cyanide detection and determination. However, this simple compound may have ...